Interaction of prostaglandins with blood plasma proteins. Comparative binding of prostaglandins A2, F2α and E2 to human plasma proteins
نویسندگان
چکیده
منابع مشابه
Interaction of Prostaglandins with Blood Plasma Proteins COMPARATIVE BINDING OF PROSTAGLANDINS A2, F20, AND E2 TO HUMAN PLASMA PROTEINS By AMIRAM RAZ
1. The binding of prostaglandin A2 and prostaglandin F2, to human plasma proteins was investigated by DEAE-Sephadex chromatography and polyacrylamide-gel electrophoresis. Both prostaglandins, when added to human plasma in vitro, were found to become bound mainly to plasma albumin. 2. The extent of binding of prostaglandins added to human plasma in low to moderate concentrations was found to be ...
متن کاملAbnormal Expression of Prostaglandins E2 and F2α Receptors and Transporters in Patients with Endometriosis
OBJECTIVE To investigate the level of expression of prostaglandin receptivity and uptake factors in eutopic and ectopic endometrium of women with endometriosis. DESIGN Prospective study. SETTING Human reproduction research laboratory. PATIENTS Seventy-eight patients with endometriosis and thirty healthy control subjects. INTERVENTION(S) Endometrial and endometriotic tissue samples were ...
متن کاملIsolation and Identification of Prostaglandins from Human Seminal Plasma. 18. Prostaglandins and Related Factors.
A depressor substance which stimulates smooth muscle was discovered by Goldblatt and von Euler in extracts of human seminal plasma and of the vesicular glands of sheep (1,Z). The active principle, called prostaglandin, wm shown to have acidic properties. Investigations on its occurrence and biological effects were carried out by von Euler (2) and more recently by El&son (3). Two biologically ac...
متن کاملInteraction of curcumin nanoformulations with human plasma proteins and erythrocytes
BACKGROUND Recent studies report curcumin nanoformulation(s) based on polylactic-co-glycolic acid (PLGA), β-cyclodextrin, cellulose, nanogel, and dendrimers to have anticancer potential. However, no comparative data are currently available for the interaction of curcumin nanoformulations with blood proteins and erythrocytes. The objective of this study was to examine the interaction of curcumin...
متن کاملBinding of hepcidin to plasma proteins.
The hepcidin hormone of 25 amino acid residues (hepcidin25) is a key regulator of iron homeostasis (1 ). Hepcidin has been shown to bind in vitro to 2macroglobulin ( 2M) and albumin in human plasma (2 ). It is not known, however, to what extent hepcidin is bound to proteins in vivo. For purposes of clinical interpretation, it is critical to know whether protein-bound or free hepcidin is being q...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1972
ISSN: 0306-3283
DOI: 10.1042/bj1300631